Single dose of green tea extract decreases lipid digestion and absorption from a test meal in humans.

Jarosław Walkowiak; Joanna Bajerska; Angelika Kargulewicz; Aleksandra Lisowska; Gwidon Siedlerski; Tomasz Szczapa; Natalia Kobelska-Dubiel; Marian Grzymisławski

doi:10.18388/abp.2013_2010

Jarosław Walkowiak Department of Pediatric Gastroenterology & Metabolic Diseases, Poznan University of Medical Sciences and Department of Human Nutrition and Hygiene, Poznan University of Life Sciences, Poznań, Poland.;
Joanna Bajerska
Angelika Kargulewicz
Aleksandra Lisowska
Gwidon Siedlerski
Tomasz Szczapa
Natalia Kobelska-Dubiel
Marian Grzymisławski

DOI: https://doi.org/10.18388/abp.2013_2010

Abstract

Green tea is known worldwide for its high content of polyphenolic compounds and multifactorial beneficial effects on human health. The role of green tea as an inhibitor of lipid hydrolysis is widely discussed. The aim of the study was to assess the influence of green tea extract on lipid digestion and absorption. The study comprised 32 healthy volunteers aged 23 to 30 years with normal exocrine pancreatic function. In all subjects (13)C-labelled mixed triglyceride breath test was performed twice with and without green tea extract ingestion. Cumulative percentage dose recovery was considered to reflect digestion and absorption of lipids. Values are expressed as medians and 1st-3rd quartile distribution. In all subjects, cumulative percentage dose recovery values were normal in a placebo test (36.8% <30.1-43.3%>). These results were significantly higher (p=0.021) than those obtained in green tea extract test (28.8% <23.1-37.2%>). Results of six tests with GTE were abnormal. Single dose of green tea extract taken with a test meal decreases lipid digestion and absorption in humans.