Chemical synthesis of dolichyl phosphates, their analogues and derivatives and application of these compounds in biochemical assays.

Leonid L Danilov; Tatyana N Druzhinina

doi:10.18388/abp.2007_3135

Chemical synthesis of dolichyl phosphates, their analogues and derivatives and application of these compounds in biochemical assays.

Leonid L Danilov N.K. Kochetkov Laboratory of Carbohydrate Chemistry, N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia.;
Tatyana N Druzhinina

DOI: https://doi.org/10.18388/abp.2007_3135

Abstract

Several methods for simple and efficient chemical synthesis of dolichyl phosphates and their analogues and derivatives are briefly summarized with a special emphasis on chemical modification of phosphoryl group and preparation of dolichyl phosphates labelled at the omega-end and at the gamma-isoprene unit of the isoprene chain by fluorescent groups, 2-aminopyridine and 1-aminonaphtalene residues. Additionally, data on biochemical assays with application of the compounds mentioned above are presented.

Published

2007-12-13

Issue

Vol. 54 No. 4 (2007)

Section

Articles

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