New cationic polyprenyl derivative proposed as a lipofecting agent.

Zbigniew Madeja; Monika Rak; Ewa Wybieralska; Igor Rózański; Marek Masnyk; Marek Chmielewski; Robert Lysek; Tadeusz Chojnacki; Wiesław Jankowski; Ewa Ciepichal; Ewa Swiezewska; Michael Tekle; Gustav Dallner

doi:10.18388/abp.2007_3191

New cationic polyprenyl derivative proposed as a lipofecting agent.

Zbigniew Madeja Department of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland. z.madeja@uj.edu.pl;
Monika Rak
Ewa Wybieralska
Igor Rózański
Marek Masnyk
Marek Chmielewski
Robert Lysek
Tadeusz Chojnacki
Wiesław Jankowski
Ewa Ciepichal
Ewa Swiezewska
Michael Tekle
Gustav Dallner

DOI: https://doi.org/10.18388/abp.2007_3191

Abstract

Cationic linear poly-cis-isoprenoid prepared from natural plant polyprenol in a mixture with dioleyl phosphatidylethanolamine was found to be an effective lipofection agent for eukaryotic cells. The transfecting activity is related to the poly-cis structure of the polyprenyl chain.

Published

2007-12-08

Issue

Vol. 54 No. 4 (2007)

Section

Articles

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