A novel polypeptide from Cervus nippon Temminck proliferation of epidermal cells and NIH3T3 cell line.

Shu-Wen Guan; Leng-Xin Duan; Yuan-Yuan Li; Ben-Xiang Wang; Qiu-Li Zhou

doi:10.18388/abp.2006_3354

A novel polypeptide from Cervus nippon Temminck proliferation of epidermal cells and NIH3T3 cell line.

Shu-Wen Guan Laboratory of Biological Macromolecule, College of Life Science, Changchun, China.;
Leng-Xin Duan
Yuan-Yuan Li
Ben-Xiang Wang
Qiu-Li Zhou

DOI: https://doi.org/10.18388/abp.2006_3354

Abstract

A novel polypeptide, velvet antler polypeptide (VAPPs), having a stimulary effect on proliferation of some cell was isolated from the velvet antler of sika deer (Cervus nippon Temminck). This polypeptide consists of a single chain of 32 amino-acid residues VLSAT DKTNV LAAWG KVGGN APAFG AEALE RM. VAPPs showed marked stimulary effect on rat epidermal cells and NIH3T3 cell line (dose range from 10-40 mg x L(-1) and 5-80 mg x L(-1), respectively).

Published

2006-06-12

Issue

Vol. 53 No. 2 (2006)

Section

Articles

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