Molecular simulation of adsorption from dilute solutions.

Werner Billes; Rupert Tscheliessnig; Johann Fischer

doi:10.18388/abp.2005_3431

Molecular simulation of adsorption from dilute solutions.

Werner Billes Institut für Verfahrens- und Energietechnik, Universität für Bodenkultur, Vienna, Austria. werner.billes@boku.ac.at;
Rupert Tscheliessnig
Johann Fischer

DOI: https://doi.org/10.18388/abp.2005_3431

Abstract

Adsorption of biomolecules on surfaces is a perennial and general challenge relevant to many fields in biotechnology. A change of the Helmholtz free energy DeltaA takes place when a molecule becomes adsorbed out of a bulk solution. The purpose of our investigations is to explore routes for the calculation of DeltaA by molecular simulations. DeltaA can be obtained both by integration over the mean force on a molecule and via the local density. It turns out that the route via the potential of mean force prevails over the latter due to better consistency. In this work we present results for systems of 1-centre and 2-centre Lennard-Jones mixtures at a 9/3 Lennard-Jones wall.

Published

2005-08-04

Issue

Vol. 52 No. 3 (2005)

Section

Articles

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