Structure and functions of tumor necrosis factor-alpha converting enzyme.

Renata Mezyk; Monika Bzowska; Joanna Bereta

doi:10.18388/abp.2003_3656

Structure and functions of tumor necrosis factor-alpha converting enzyme.

Renata Mezyk Department of Cell Biochemistry, Faculty of Biotechnology, Jagiellonian University, Kraków, Poland.;
Monika Bzowska
Joanna Bereta

DOI: https://doi.org/10.18388/abp.2003_3656

Abstract

Tumor necrosis factor-alpha converting enzyme (TACE) is the first described and best characterized secretase. In this review the structure and the possible roles for TACE are summarized. The substrate specificity and the regulation of TACE activity as well as redundancy and possible cooperations of distinct secretases are also discussed.

Published

2003-09-30

Issue

Vol. 50 No. 3 (2003)

Section

Articles

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