The structure of the Ca2+-ATPase of sarcoplasmic reticulum.

Anthony N Martonosi; Slawomir Pikula

doi:10.18388/abp.2003_3690

The structure of the Ca2+-ATPase of sarcoplasmic reticulum.

Anthony N Martonosi Upstate Medical University, College of Graduate Studies, State University of New York, Syracuse, NY, U.S.A.;
Slawomir Pikula

DOI: https://doi.org/10.18388/abp.2003_3690

Abstract

In this article the morphology of sarcoplasmic reticulum, classification of Ca(2+)-ATPase (SERCA) isoenzymes presented in this membrane system, as well as their topology will be reviewed. The focus is on the structure and interactions of Ca(2+)-ATPase determined by electron and X-ray crystallography, lamellar X-ray and neutron diffraction analysis of the profile structure of Ca(2+)-ATPase in sarcoplasmic reticulum multilayers. In addition, targeting of the Ca(2+)-ATPase to the sarcoplasmic reticulum is discussed.

Published

2003-06-30

Issue

Vol. 50 No. 2 (2003)

Section

Articles

Acta Biochimica Polonica is an OpenAccess quarterly and publishes four issues a year. All contents are distributed under the Creative Commons Attribution-ShareAlike 4.0 International (CC BY 4.0) license. Everybody may use the content following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.