Sequence analysis of enzymes with asparaginase activity.

D Borek; M Jaskólski

doi:10.18388/abp.2001_3855

Sequence analysis of enzymes with asparaginase activity.

D Borek Department of Crystallography, Faculty of Chemistry, A. Mickiewicz University, Poznań, Poland.;
M Jaskólski

DOI: https://doi.org/10.18388/abp.2001_3855

Abstract

Asparaginases catalyze the hydrolysis of asparagine to aspartic acid and ammonia. Enzymes with asparaginase activity play an important role both in the metabolism of all living organisms as well as in pharmacology. The main goal of this paper is to attempt a classification of all known enzymes with asparaginase activity, based on their amino acid sequences. Some possible phylogenetic consequences are also discussed using dendrograms and structural information derived from crystallographic studies.

Published

2001-12-31

Issue

Vol. 48 No. 4 (2001)

Section

Articles

Acta Biochimica Polonica is an OpenAccess quarterly and publishes four issues a year. All contents are distributed under the Creative Commons Attribution-ShareAlike 4.0 International (CC BY 4.0) license. Everybody may use the content following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.