Saccharomyces cerevisiae--a model organism for the studies on vacuolar transport.

  • R Kucharczyk Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warszawa.;
  • J Rytka

Abstract

The role of the yeast vacuole, a functional analogue of the mammalian lysosome, in the turnover of proteins and organelles has been well documented. This review provides an overview of the current knowledge of vesicle mediated vacuolar transport in the yeast Saccharomyces cerevisiae cells. Due to the conservation of the molecular transport machinery S. cerevisiae has become an important model system of vacuolar trafficking because of the facile application of genetics, molecular biology and biochemistry.
Published
2001-12-31
Section
Articles