Activity of glycogen depolymerizing enzymes in extracts from brain tumor tissue (anaplastic astrocytoma and glioblastoma multiforme).

B Kotoński; J Wilczek; J Madej; A Zarzycki; J Hutny

doi:10.18388/abp.2001_3869

Activity of glycogen depolymerizing enzymes in extracts from brain tumor tissue (anaplastic astrocytoma and glioblastoma multiforme).

B Kotoński Department of Biochemistry, Agricultural University of Wroclaw, Poland.;
J Wilczek
J Madej
A Zarzycki
J Hutny

DOI: https://doi.org/10.18388/abp.2001_3869

Abstract

An approximately threefold increase in glycogenolytic activity of the neutral alpha-1,4-glucosidase and a twofold increase in the same activity of the acid isoform have been found in extracts of anaplastic astrocytoma and glioblastoma multiforme tumors of brain tissue. "Maltase activity" of the respective enzymes increased by 60-80% in both kinds of tumor extracts. However a significant decrease in a-amylase and almost complete disappearance of phosphorylase activities have also been found in both kinds of tumors.

Published

2001-12-31

Issue

Vol. 48 No. 4 (2001)

Section

Articles

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