Synthesis and application of chiral triazine condensing reagents prepared from esters of amino acids.

Z J Kamiński; K J Zajac; K Jastrzabek

doi:10.18388/abp.2001_3880

Synthesis and application of chiral triazine condensing reagents prepared from esters of amino acids.

Z J Kamiński Institute of Organic Chemistry, Technical University of Lódź, Poland. kaminsz@ck-sg.p.lodz.pl;
K J Zajac
K Jastrzabek

DOI: https://doi.org/10.18388/abp.2001_3880

Abstract

Treatment of cyanuric chloride with chiral amines or esters of chiral amino acids gave chiral 2,4-dichloro-6-alkylamino-1,3,5-triazines (2-5) in 49-69% yield, which were found useful as coupling reagents. Enantioselective activation and enantioselective aminolysis in the presence of 2-5 was observed.

Published

2001-12-31

Issue

Vol. 48 No. 4 (2001)

Section

Articles

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