Novel side reactions accompanying activation and aminolysis of N-benzoyl-2-alkylserines.

Z J Kamiński; A Woszczyna; B Kolesińska; A Redliński

doi:10.18388/abp.2001_3887

Novel side reactions accompanying activation and aminolysis of N-benzoyl-2-alkylserines.

Z J Kamiński Institute of Organic Chemistry, Technical University of Lódź, Poland. kaminsz@ck-sg.p.lodz.pl;
A Woszczyna
B Kolesińska
A Redliński

DOI: https://doi.org/10.18388/abp.2001_3887

Abstract

2-Phenyl-4-alkyl-4-hydroxymethyl-1,3-oxazolones (2a-d) have been identified as side products accompanying activation of N-benzoyl-2-alkylserines (1a-d). Oxazolones 2a-d in the presence of amine rearrange subsequently to corresponding 4-alkyl-2-phenyl-4,5-dihydro-1,3-oxazole-5 carboxylic acids (4a-d) at a 20-68% yield.

Published

2001-12-31

Issue

Vol. 48 No. 4 (2001)

Section

Articles

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