Conformational properties of N',N'-dimethylamides of N-acetyldehydroalanine and N-acetyl-(Z)-dehydrophenylalanine.

D Siodłak; M A Broda; B Rzeszotarska; A E Kozioł; I Dybała

doi:10.18388/abp.2001_3888

Conformational properties of N',N'-dimethylamides of N-acetyldehydroalanine and N-acetyl-(Z)-dehydrophenylalanine.

D Siodłak Institute of Chemistry, University of Opole, Poland.;
M A Broda
B Rzeszotarska
A E Kozioł
I Dybała

DOI: https://doi.org/10.18388/abp.2001_3888

Abstract

Conformational preferences of Ac-deltaAla-NMe2 and Ac-(Z)-deltaPhe-NMe2 were studied and compared with those of their monomethyl counterparts as well as with those of their saturated analogues. X-Ray data and energy calculations revealed a highly conservative conformation of the dehydro dimethylamides, which is located in a high-energy region of the Ramachandran map.

Published

2001-12-31

Issue

Vol. 48 No. 4 (2001)

Section

Articles

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