Hematological and antifungal properties of temporin A and a cecropin A-temporin A hybrid.

D Wade; A Silveira; L Rollins-Smith; T Bergman; J Silberring; H Lankinen

doi:10.18388/abp.2001_3889

Hematological and antifungal properties of temporin A and a cecropin A-temporin A hybrid.

D Wade Peptide Laboratory, Haartman Institute, Helsinki University, Finland. wade@cc.helsinki.fi;
A Silveira
L Rollins-Smith
T Bergman
J Silberring
H Lankinen

DOI: https://doi.org/10.18388/abp.2001_3889

Abstract

Temporin A (TA) and a cecropin A-temporin A hybrid peptide (CATA) were synthesized and assayed for their hemolytic, anticoagulant, and antifungal properties. CATA retains significant antifungal activity, is less hemolytic than TA, and inhibits blood coagulation. These results recommend further studies of the biological activities of CATA.

Published

2001-12-31

Issue

Vol. 48 No. 4 (2001)

Section

Articles

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