The left-handed double helical nucleic acids.

B A Brown; A Rich

doi:10.18388/abp.2001_3916

The left-handed double helical nucleic acids.

B A Brown Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA.;
A Rich

DOI: https://doi.org/10.18388/abp.2001_3916

Abstract

The conversion of right-handed dsDNA and dsRNA to the left-handed Z-conformation involves a reorganization of the nucleotides relative to each other. This conversion can be facilitated by the tight binding of a Z-conformation-specific protein domain from the editing enzyme dsRNA adenosine deaminase. This may influence the modification of both pre-mRNAs as well as some replicating RNA viruses.

Published

2001-06-30

Issue

Vol. 48 No. 2 (2001)

Section

Articles

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