Elements of thermodynamics in RNA evolution.

E Kierzek; E Biała; R Kierzek

doi:10.18388/abp.2001_3932

Elements of thermodynamics in RNA evolution.

E Kierzek Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznań. rkierzek@ibch.poznan.pl;
E Biała
R Kierzek

DOI: https://doi.org/10.18388/abp.2001_3932

Abstract

The paper presents some aspects correlating thermal stability of RNA folding and the occurrence of structural motifs in natural ribonucleic acids. Particularly, the thermodynamic stability of 2'-5' and 3'-5' linked RNA and the contribution of unpaired terminal nucleotides (dangling ends) in secondary (2D) and tertiary (3D) structures of RNA are discussed. Both examples suggest that during evolution nature selected sequences and structures of RNA which are the most thermally stable and efficient for their biological function.

Published

2001-06-30

Issue

Vol. 48 No. 2 (2001)

Section

Articles

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