Motifs of the caldesmon family.

E A Czuryło

doi:10.18388/abp.2000_3955

Motifs of the caldesmon family.

E A Czuryło Nencki Institute of Experimental Biology, Department of Muscle Biochemistry, Warszawa, Poland. eczurylo@nencki.gov.pl;

DOI: https://doi.org/10.18388/abp.2000_3955

Abstract

Seven highly conserved regions were found in caldesmon molecules from various sources using the multiple sequence alignment method. Their localization coincides with regions where the binding sites to other proteins were postulated. Less conserved and highly divergent regions of the sequences are described as well. These results could refine the planning of caldesmon gene manipulations and accelerate the precise localization of binding sites in the caldesmon molecule and, as a consequence, this could help to elucidate its function in smooth muscle contraction.

Published

2000-12-31

Issue

Vol. 47 No. 4 (2000)

Section

Articles

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