Translational frameshift sites within bacteriophage lambda genes rexA and cI.

  • S Hayes Department of Microbiology, College of Medicine, University of Saskatchewan, Saskatoon, Canada.;
  • H J Bull

Abstract

Phage lambda's cI-rexA-rexB operon displays an intriguing example of regulation by an unexplained mechanism of polarity. We have identified three potential -1 translational frameshift sites and present a model for translational frameshift suppression by lambda's CI repressor as a mechanism of regulating operon polarity, implying an additional role for CI self-regulation.
Published
1999-12-31
Section
Articles