Anticoagulative effect of pepsin.

  • M Gacko Department of Instrumental Analysis, Medical Academy, Białystok, Poland.;
  • W Roszkowska-Jakimiec
  • J Jasielczuk

Abstract

Anticoagulative effect of pepsin is observed in vitro when its concentration is 36 microM and higher. This effect is due to inhibition of fibrin monomer polymerization. Protamine abolishes anticoagulative effect of pepsin. Pepsin does not influence platelet aggregation induced by ADP and collagen.
Published
1999-09-30
Section
Articles