Lack of squamous cell lung carcinoma in vitro chemosensitivity to various drug regimens in the adenosine triphosphate cell viability chemosensitivity assay.

U Vogt; E Striehn; U Bosse; F Klinke; B Falkiewicz

doi:10.18388/abp.1999_4163

Lack of squamous cell lung carcinoma in vitro chemosensitivity to various drug regimens in the adenosine triphosphate cell viability chemosensitivity assay.

U Vogt European Laboratory Association Section Ibbenbüren, Germany. DRUVOGT@t-online.de;
E Striehn
U Bosse
F Klinke
B Falkiewicz

DOI: https://doi.org/10.18388/abp.1999_4163

Abstract

A pilot study on squamous cell lung carcinoma (LC) chemosensitivity in adenosine triphosphate cell viability chemosensitivity assay (ATP-CVA) was performed. Besides the histological investigation, a modified ATP-CVA was used for the analysis of cancer cell chemosensitivity to four drug regimens, including topotecan, a promising agent for non-small-cell lung cancer (NSCLC) chemotherapy. Results of in vitro chemosensitivity testing showed chemoresistance or only weak response in the predominant amount of tumors.

Published

1999-06-30

Issue

Vol. 46 No. 2 (1999)

Section

Articles

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