Implication of glycolipids in lens fiber development.

M Ogiso

doi:10.18388/abp.1998_4243

Implication of glycolipids in lens fiber development.

M Ogiso Cell and Information, PRESTO, Japan Science and Technology Corporation. mogiso@bio.titech.ac.jp;

DOI: https://doi.org/10.18388/abp.1998_4243

Abstract

Mammalian lens contains Lewis(x), sialyl-Lewis(x) and alpha-galactosyl epitopes in neolactoseries glycosphingolipids. The expression of these three epitopes is not observed in lens epithelial cells, but is immunohistochemically detected in the inner cortical fibers and the lens nucleus. In embryonic chick lens, sialyl-Lewis(x)-containing gangliosides were also detected in the transitional zone and elongating lens fibers. Thus, the Lewis(x), sialyl-Lewis(x) and alpha- galactosyl epitopes may be associated with the differentiation and maturation of lens epithelial cells to lens fibers.

Published

1998-06-30

Issue

Vol. 45 No. 2 (1998)

Section

Articles

Acta Biochimica Polonica is an OpenAccess quarterly and publishes four issues a year. All contents are distributed under the Creative Commons Attribution-ShareAlike 4.0 International (CC BY 4.0) license. Everybody may use the content following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.