Prostatic acid phosphatase: structural aspects of inhibition by L-(+)-tartrate ions.

L Lovelace; K Lewiński; C G Jakob; R Kuciel; W Ostrowski; L Lebioda

doi:10.18388/abp.1997_4369

Prostatic acid phosphatase: structural aspects of inhibition by L-(+)-tartrate ions.

L Lovelace Department of Chemistry and Biochemistry, University of South Carolina, Columbia 29208, USA.;
K Lewiński
C G Jakob
R Kuciel
W Ostrowski
L Lebioda

DOI: https://doi.org/10.18388/abp.1997_4369

Abstract

The crystal structure of the complex between rat-prostatic acid phosphatase (PAP) and L-(+)-tartrate (Lindqvist et al., J. Biol. Chem., 1993, 268, 20744-20746) contains the model of the ligand with incorrect chirality. We report here the correct model and discuss the relation between this model and the model of the inhibitory complexes between PAP and oxy-anions.

Published

1997-12-31

Issue

Vol. 44 No. 4 (1997)

Section

Articles

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