Activity of liver proteases in experimental methanol intoxication.

  • E Skrzydlewska Department of Instrumental Analysis, Medical Academy, Białystok, Poland.;
  • Z Skrzydlewski
  • K Worowski

Abstract

Intoxication of rats with methanol (1.5 and 3.0 g/kg body weight) led to a significant, time- and dose-dependent decrease in the activities of cathepsins A, B and C, while the activity of cathepsin D was unaffected. The decrease was associated with a different partial release of individual cathepsins to the post-lysosomal fraction.
Published
1997-06-30
Section
Articles