Nucleotide sequence of c-H-ras-1 gene from B6C3F1 mice.

B Przybojewska; G Płucienniczak

doi:10.18388/abp.1996_4493

Nucleotide sequence of c-H-ras-1 gene from B6C3F1 mice.

B Przybojewska Department of Toxicological Biochemistry, Institute of Occupational Medicine, Lódź, Poland.;
G Płucienniczak

DOI: https://doi.org/10.18388/abp.1996_4493

Abstract

The c-H-ras-1 gene of an B6C3F1 mouse was isolated and nucleotide sequence determined. Our study has revealed that this c-H-ras-1 gene consists of four exons, separated by three introns ranging in size from 150 to 649 bp. The coding parts of the sequence of mouse c-H-ras-1 gene show no important differences as compared with those of the rat, hamster and human gene. More numerous changes were found in introns. The identity of mouse c-H-ras-1 gene with rat, hamster and human ones at the nucleotide level is 86.40%, 80.04% and 67.87%, respectively. Comparison of amino acids in protein sequence of c-H-ras gene of mouse, rat, hamster and human points to high degree of conservation of the gene.

Published

1996-09-30

Issue

Vol. 43 No. 3 (1996)

Section

Articles

Acta Biochimica Polonica is an OpenAccess quarterly and publishes four issues a year. All contents are distributed under the Creative Commons Attribution-ShareAlike 4.0 International (CC BY 4.0) license. Everybody may use the content following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.