Modified substrates of DNA polymerases and design of antivirals.

A A Krayevsky; L A Alexandrova; N B Dyatkina; M K Kukhanova; E A Shirokova

doi:10.18388/abp.1996_4523

Modified substrates of DNA polymerases and design of antivirals.

A A Krayevsky Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.;
L A Alexandrova
N B Dyatkina
M K Kukhanova
E A Shirokova

DOI: https://doi.org/10.18388/abp.1996_4523

Abstract

The results obtained in our laboratory on investigating of substrate properties of a large number of compounds towards different DNA polymerases have been summarized. On the basis of systematic analysis a directed synthesis of nucleotides with antiviral properties was performed.

Published

1996-03-31

Issue

Vol. 43 No. 1 (1996)

Section

Articles

Acta Biochimica Polonica is an OpenAccess quarterly and publishes four issues a year. All contents are distributed under the Creative Commons Attribution-ShareAlike 4.0 International (CC BY 4.0) license. Everybody may use the content following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.