Differences in nonenzymatic glycation of histones.

  • A Lakatos Department of Clinical Chemistry, University Medical School, Pécs, Hungary.;
  • N Kiss
  • K Jobst

Abstract

Time course of glucose binding by histone Hl and total histones was followed in isolated histone preparations and in thymus nuclei. In both cases the uptake of glucose by Hl was surprisingly high in contrast to a much lower uptake of glucose by total histones. DNA is not implicated in glycation of histones in nuclei.
Published
1994-12-31
Section
Articles