Na+,K(+)-ATPase activity of rabbit kidney cortex membranes in ischemia and reperfusion.

S Aydin; A Aricioglu; N Turkozkan; F Bingol; C Aydin

doi:10.18388/abp.1993_4796

Na+,K(+)-ATPase activity of rabbit kidney cortex membranes in ischemia and reperfusion.

S Aydin Ministry of Health, Ankara Training Hospital, Department of Biochemistry, Cebeci, Turkey.;
A Aricioglu
N Turkozkan
F Bingol
C Aydin

DOI: https://doi.org/10.18388/abp.1993_4796

Abstract

The activity of Na+,K(+)-ATPase in the microsomal fraction of rabbit kidney cortex was strongly decreased by ischemia and increased slightly, but not significantly, after reperfusion. These changes were correlated with a dramatic increase in lipid peroxidation in microsomes isolated from both ischemic and reperfused kidneys. This correlation may point to irreversible impairment of the enzymatic function under the influence of either oxygen free radicals or lipid peroxidation.

Published

1993-12-31

Issue

Vol. 40 No. 4 (1993)

Section

Articles

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